The German was the dominant power within the race on the Autodromo Hermanos Rodriguez circuit after ranging from pole and main nearly all of the laps in a largely processional affair.
He ultimately took victory by simply over one second from Envision driver and fellow front-row starter Sebastien Buemi, as Nick Cassidy took a podium on his Jaguar debut.
Reigning champion Jake Dennis may solely handle ninth, having suffered a troublesome qualifying session which left the Andretti driver 14th on the grid, and like Wehrlein stays underneath investigation for a technical infringement.
Wehrlein maintained his benefit from pole firstly, whereas behind, Buemi took to the within line to forestall Maximilian Guenther from overtaking into Flip 1 with Cassidy, Mitch Evans and Jake Hughes sustaining place off the road.
The primary of two Assault Mode activations got here as early as lap three for the leaders, with Wehrlein taking two minutes and rejoining behind Buemi, however a lap later the positions have been reversed once more, with Buemi taking six minutes of Assault Mode.
By lap six, Wehrlein had taken the remaining six minutes of his Assault Mode and as soon as once more solely misplaced one place to Buemi earlier than closely pressuring the Envision driver for the lead.
The entrance two had began to hole Guenther behind, who had the shut attentions of Cassidy to cope with because the Kiwi was the one different entrance runner other than Wehrlein to have used each Assault Modes by this level.
Picture by: Dom Romney / Motorsport Images
Pascal Wehrlein, Porsche, Porsche 99X Electrical Gen3, Sebastien Buemi, Envision Racing, Jaguar I-TYPE 6, Mitch Evans, Jaguar Racing, Jaguar I-TYPE 6, Nick Cassidy, Jaguar TCS Racing, Jaguar I-TYPE 6, Jake Hughes, McLaren, e-4ORCE 04, the remainder of the sector firstly
However the race was neutralised on lap 9 after Buemi’s Envision team-mate, Robin Frijns, misplaced management and made heavy contact with the barrier on the exit of T18.
The Dutchman had been making an attempt to recuperate floor after struggling to get off the road as a result of a technical drawback and a security automobile was deployed to recuperate his stranded machine, which was left throughout the observe.
After three laps underneath warning, and on the earliest alternative, Buemi took his remaining Assault Mode and dropped to second, with Cassidy ultimately shifting as much as third as Guenther did the identical on lap 15.
By this level the highest 9 drivers had used each activations, with Wehrlein holding a lead of virtually a second from Buemi, with Cassidy and Guenther in shut proximity.
Evans in fifth had began to regularly drop again, although, and the Jaguar driver got here underneath stress from the DS Penske of Jean-Eric Vergne who had jumped Hughes within the Assault Mode activation part.
Regardless of working nose-to-tail for the second half of the race, which was prolonged to 37 laps because of the earlier security automobile, the highest 10 positions remained unchanged till the chequered flag.
Oliver Rowland took eleventh on his return with Nissan from team-mate Sacha Fenestraz, the pair heading Edoardo Mortara (Mahindra), Sam Bird (McLaren) and Nyck de Vries (Mahindra) on his Components E return.
In addition to Frijns, different retirements included Porsche’s Antonio Felix da Costa, who broken his suspension on lap three after contact with Muller into Flip 3 – an incident which can be investigated after the race.
Muller’s team-mate Lucas di Grassi was a gap lap retirement after struggling brake issues, whereas Sergio Sette Camara was unable to start out as a result of technical points along with his ERT machine.